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Occult Mediastinal Lymph Node Metastasis in NSCLC Patients Diagnosed as Clinical N0-1 by Preoperative Integrated FDG-PET/CT and CT: Risk Factors, Pattern, and Histopathological Study - OncologySTAT

Occult Mediastinal Lymph Node Metastasis in NSCLC Patients Diagnosed as Clinical N0-1 by Preoperative Integrated FDG-PET/CT and CT: Risk Factors, Pattern, and Histopathological Study - OncologySTAT:

The present study demonstrated that adenocarcinoma, tumors located in the upper or middle lobe, tumor size >3 cm, and SUVmax of primary tumor >4.0 g/ml are risk factors for occult MLN metastasis in patients with NSCLC who were diagnosed as clinical N0-1 by preoperative integrated FDG-PET/CT and CT. Patients with tumors located in the right upper or middle lobe are considered candidates for cervical mediastinoscopy because the involved metastatic mediastinal lymph nodes are easily accessible by these modalities.