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Molecular Markers May Improve Selection of Patients With Pancreatic Cancer for Surgery - OncologySTAT

Molecular Markers May Improve Selection of Patients With Pancreatic Cancer for Surgery - OncologySTAT


...in the cohort of 372 patients who underwent surgical resection for pancreatic cancer, the markers S100A2 and S100A4, which are associated with more aggressive tumor behavior, predicted worse survival after surgery.
Median survival was almost three times longer when a tumor was immunohistochemically negative for both markers, compared with positive for S100A2 (34.3 vs. 11.9 months). A third group of patients having tumors positive only for S100A4 had intermediate survival (15.6 months)....